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Promega
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Promega
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Promega
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AJ Roboscreen GmbH
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Promega
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Image Search Results
Journal: Journal of Oncology
Article Title: Circulating Tumor DNA Using Tagged Targeted Deep Sequencing to Assess Minimal Residual Disease in Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy
doi: 10.1155/2020/8132507
Figure Lengend Snippet: Selected mutations at diagnosis by Comprehensive Cancer Panel™ on FFPE biopsies.
Article Snippet: DNA from formalin-fixed paraffin-embedded (FFPE) breast tissue samples was extracted using the
Techniques: Biomarker Discovery
Journal: Journal of Oncology
Article Title: Circulating Tumor DNA Using Tagged Targeted Deep Sequencing to Assess Minimal Residual Disease in Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy
doi: 10.1155/2020/8132507
Figure Lengend Snippet: Mutational analysis by ddPCR on FFPE biopsy and on ctDNA.
Article Snippet: DNA from formalin-fixed paraffin-embedded (FFPE) breast tissue samples was extracted using the
Techniques: Mutagenesis, Sampling
Journal: Journal of Oncology
Article Title: Circulating Tumor DNA Using Tagged Targeted Deep Sequencing to Assess Minimal Residual Disease in Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy
doi: 10.1155/2020/8132507
Figure Lengend Snippet: ddPCR anticipates clinical relapse in one patient with a TP53 mutation. (a) Assessment of target mutation by ddPCR during the monitoring on ctDNA in a patient (UPN1) relapsed at 12 months. TP53 p. Y205C c.614A>G was present at 6 months (T4) after surgery, anticipating the patient's clinical relapse by six months. (b) ddPCR scatterplot of target mutation ( y -axis) vs. wild type ( x -axis) on FFPE biopsy at diagnosis (upper plot) and on ctDNA at T4 (lower plot).
Article Snippet: DNA from formalin-fixed paraffin-embedded (FFPE) breast tissue samples was extracted using the
Techniques: Mutagenesis, Biomarker Discovery
Journal: Journal of Oncology
Article Title: Circulating Tumor DNA Using Tagged Targeted Deep Sequencing to Assess Minimal Residual Disease in Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy
doi: 10.1155/2020/8132507
Figure Lengend Snippet: Mutational analysis by MPS and tTDS on FFPE biopsy, comparison between MPS and tTDS on FFPE biopsies samples at diagnosis.
Article Snippet: DNA from formalin-fixed paraffin-embedded (FFPE) breast tissue samples was extracted using the
Techniques: Comparison, Biomarker Discovery, Mutagenesis
Journal: Journal of Oncology
Article Title: Circulating Tumor DNA Using Tagged Targeted Deep Sequencing to Assess Minimal Residual Disease in Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy
doi: 10.1155/2020/8132507
Figure Lengend Snippet: Mutational analysis by tTDS on ctDNA.
Article Snippet: DNA from formalin-fixed paraffin-embedded (FFPE) breast tissue samples was extracted using the
Techniques:
Journal: Journal of Oncology
Article Title: Circulating Tumor DNA Using Tagged Targeted Deep Sequencing to Assess Minimal Residual Disease in Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy
doi: 10.1155/2020/8132507
Figure Lengend Snippet: Comparison case in point of MPS, MPS, and tTDS for mutation tracking: PIK3CA mutation H1047R could be detected in plasma and in the FFPE pretreatment biopsy by MPS, ddPCR, and tTDS. However, ddPCR allowed the detection of such mutation only at baseline, whereas by tTDS we could track the presence of H1047R six months before relapse.
Article Snippet: DNA from formalin-fixed paraffin-embedded (FFPE) breast tissue samples was extracted using the
Techniques: Comparison, Mutagenesis, Clinical Proteomics